Search on: RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES 
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Descriptor English:   Receptor-Interacting Protein Serine-Threonine Kinases 
Descriptor Spanish:   Proteína Serina-Treonina Quinasas de Interacción con Receptores 
Descriptor Portuguese:   Proteína Serina-Treonina Quinases de Interação com Receptores 
Synonyms English:   RIP Serine-Threonine Kinases  
Tree Number:   D08.811.913.696.620.682.700.801
D12.644.360.024.296.400
D12.644.360.024.500.186
D12.644.360.075.421.400
D12.776.157.057.024.400
D12.776.157.057.500.186
D12.776.476.024.375.662
D12.776.476.024.500.186
D12.776.476.075.421.400
Definition English:   A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment. 
History Note English:   2007(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52250 
Unique Identifier:   D053422 

Occurrence in VHL: 		 

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